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KMID : 0882419930440010086
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Korean Journal of Medicine
1993 Volume.44 No. 1 p.86 ~ p.92
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Vitamin C Concentration of Gastric Juice, Plasma, and Urine in Various Gastric Diseases
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이삼철
정판준/이옥재/김영채/최진학/하우송
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Abstract
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he level of vitamin C was measured from the specimens of plasms, gastric juice, and urine of the symptom-fredd subjects of chronic superficial gastritis and other gastric : diseases by 2,4-dinitrophenylhydrazine method. The
object
of
this study is to know the relationship between vitamin C concentration of tissue fluids and gastric diseases.
Following results have been obtained:
1) the levels of vitamin C in the gastric juice of the patients of symptomaitc chronic
superficial gastritis, chronic atrophic gastritis and metaplastic gastritis, gastric ulcer, and
gastric cancer were lower than those of the symptom-free subjects of chronic superficial
gastritis and in the case of the patients with gastric cancer, the level was the lowest.
2) the plasma level of vitamin C concentration was not different among the
specimens from the groups of the patients.
3) in the case of hypochlorhydria(pH>4.0), the level of vitamin C concerntrations were not
different, compaired to that of the patients with gastric pH below 4.0.
4) the ratios of the gastric juice to plasma vitamin C concentrations was low in the
groups of symptomatic chronic superficial gastritis, chronic atrophic gastritis and
metaplastic gastritis, and gastric cancer, but the ratios were not low in patients of acute
gastrits and gastric ulcer, compared to the symptom-free subjects of chronic superficial
gastritis(p<0.05).
5) the ratios of the urine to plasma vitamin C concentrations in the groups of various
gastric dieases were not different ot those of the symptom-free subjects of chronic superficial
gastritis.
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KEYWORD
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